What must veterinarians consider when determining a drug's therapeutic range?

When veterinarians determine a drug's therapeutic range, they must consider both the species and weight of the animal. The therapeutic range refers to the concentration of a drug in the bloodstream that is effective without being toxic. Different species metabolize drugs at varying rates due to differences in their physiology, biochemistry, and even behavior. For instance, what is an appropriate dosage for a dog may not be suitable for a cat, as these species have different sensitivities and capacity to metabolize certain medications.

Additionally, weight is a critical factor since dosages are often calculated based on the animal's body weight. An accurate understanding of the animal’s weight ensures that the veterinarian can administer an effective dose, minimizing the risk of underdosing or overdosing. By integrating both species information and the specific weight of the patient into their calculations, veterinarians can maximize therapeutic effects while minimizing adverse reactions, ultimately contributing to better patient outcomes.